Using texture and fractal analysis for classification of cell nuclei from light scattering spectroscopic images

Abstract

The paper presents an original experimental optical LSS system which allows backscattering Mie diffusion spectra determination for biological samples. With the aim of evaluating viral infection effects, a software package performs fractal analysis of the spectra and texture analysis of the associated microscopic images. Finally a method for the classification of cell nuclei and the discrimination between virus infected and non-infected biological samples using a combined vector of the computed fractal and texture features is proposed.