INVESTIGATION OF NEW ASPERGILLUS STRAINS AS PRODUCERS OF HEMOSTATICALLY ACTIVE PROTEASES

Abstract

For ve species of Aspergillus micromycetes, the diversity of proteolytic activities against human hemostasis proteins was assessed. For every strain, absence of activities similar to hemostatic proteases - thrombin, plasmin, factor Xa, urokinase, and protein C was shown. In addition, no activating activities towards precursors of the named proteases were demonstrated. For A. glaucus, proteases of high activity (58,52 Utyr) and speci city against brinogen were found. A. athecius, A. caespitosus и A. wentii, were capable of proteolysis at acidic pH.