Evaluation of Lipid Profile and Some Hematological Parameters of Albino Rats Fed With Honey

C. Nwozor, E. Alagwu, P. O. Nwabuokei, E. C. Okonobe, H. O. Enwelum
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Abstract

Honey is widely consumed in Nigeria. Its main uses include wound healing, baking, and as an addition to various beverages. This study was undertaken to investigate the effect, of honey on lipid profile and some hematological parameters of adult albino rats. Sixteen adult albino rats were randomly divided into two groups. Group A {8 rats) served as control and received rat chow and water only. Group B (8 rats) received 1ml of honey per rat per day for three weeks. Thereafter, the animals were anaesthetized with chloroform. Blood samples were collected for analysis via cardiac puncture. The results showed that honey increased HDL and decreased LDL in group B. Increase in triglycerides in group B was not significant. It had no effect on cholesterol and VLDL in group B. Honey had no effect on PCV, monocytes, eosinophils, basophils. In group B, changes in lymphocytes and neutrophils were not significant. It increased total WBC. If applied to human, moderate intake of honey may help prevent the risk of atherosclerosis.
白化病大鼠喂蜂蜜后血脂及一些血液学指标的评价
蜂蜜在尼日利亚被广泛消费。它的主要用途包括伤口愈合,烘焙,以及作为各种饮料的添加剂。本研究旨在探讨蜂蜜对成年白化病大鼠血脂及部分血液学指标的影响。16只成年白化大鼠随机分为两组。A组(8只)为对照组,只给予大鼠饲料和水。B组(8只大鼠)每只大鼠每天给予1ml蜂蜜,连续三周。之后,用氯仿麻醉动物。通过心脏穿刺采集血液样本进行分析。结果表明,蜂蜜使B组的HDL升高,LDL降低。B组的甘油三酯升高不显著。对b组胆固醇和VLDL无影响。蜂蜜对PCV、单核细胞、嗜酸性粒细胞、嗜碱性粒细胞无影响。B组淋巴细胞和中性粒细胞变化不显著。它增加了总白细胞。如果适用于人类,适量摄入蜂蜜可能有助于预防动脉粥样硬化的风险。
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