Data analisis of 4D phase contrast MRI in healthy and non-healthy patients

E. Soudah, M. Bordone, Marcelino Rodriguez, Jorge S. Perez, C. Li, F. Carreras
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Abstract

Time-resolved, 3-dimensional phase-contrast magnetic resonance imaging (3D+t PCMRI) is employed to obtain complete spatial and temporal coverage of the vessels blood combined with spatially registered 3-directional pulsatile blood flow velocities[1][2]. Recent studies have reported that Wall Shear Stress (WSS) quantification from PCMRI are able to use the WSS as biomarkers for different aortas pathologies [3]. Figure [1] shows the pathline visualization of blood flow during one cardiac cycle in the heart of a healthy patient at peak early LV filling, diastasis, peak atrial contraction, and peak systole.
健康与非健康患者的4D相衬MRI数据分析
采用时间分辨的三维相对比磁共振成像(3D+t PCMRI),结合空间记录的3向脉动血流速度,获得血管血液的完整时空覆盖[1][2]。最近的研究报道,PCMRI的壁剪切应力(Wall Shear Stress, WSS)量化能够将WSS作为不同主动脉病理的生物标志物[3]。图[1]显示了健康患者心脏在早期左室充盈高峰、舒张高峰、心房收缩高峰和收缩高峰时一个心动周期内的血流路径可视化。
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