O. Yakovlev, M. Vakhviyaynen, M. A. Judin, A. Anokhin, A. Konovalov
{"title":"The problem of the course reception of sympatomimetics from the group of aliphatic amines safety (geranamine, octodrine, AMP citrate)","authors":"O. Yakovlev, M. Vakhviyaynen, M. A. Judin, A. Anokhin, A. Konovalov","doi":"10.47529/2223-2524.2021.4.7","DOIUrl":null,"url":null,"abstract":"Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.","PeriodicalId":309619,"journal":{"name":"Sports medicine: research and practice","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sports medicine: research and practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47529/2223-2524.2021.4.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.