Enhancement of doxorubicin effect on cancer cell mortality with ultrasound and microbubbles

Abstract

Doxorubicin is an important potent anti-cancer drug and is used for the treatment of various malignancies. Although its effectiveness is proved, its adverse effects are regarded as a problem. Ultrasound and microbubbles are considered as a potent method to enhance doxorubicin effect by reducing the dose of administered drug and thus its side effects.