Role of CD4 T-regulator cell and their subsets in bladder cancer

Abstract

Tumor-infiltrating lymphocytes (TILs) are candidate as crucial biomarkers since certain cancers have high lymphocyte infiltration that obtain significant role in specific cancer types that can be contributed in tumor pathogenesis. In Bladder cancer found to be highly infiltrated with T-regulator cells, and it has been found to be associated with tumor progression and poor disease outcome as well. In this study, we assess the CD4 T- regulator cells and their subsets infiltration in tumor and autologous normal microenvironments of the urinary bladder and sub