Immunological Response to Respiratory Syncytial Virus Infection

Abstract

Immunological response to Respiratory Syncytial Virus (RSV) involves multiple entities such as cellular, antibody, cytokine, chemokine, and Pattern Recognizing Receptors (PRRs) that are mobilized to subdue the airway and pulmonary effects of the virus. RSV predominantly involves the respiratory tract including the bronchioles and the lungs in addition to the upper respiratory passage. Although RSV afflicts all age groups predominantly in winter, severe infection is more common in the very young and in older individuals, i.e., 60-65 years of age. Recently, vaccines and monoclonal antibodies have been developed as a preventive strategy for the vulnerable.