El-Ayak ve Ağız Hastalığında Ortalama Trombosit Hacmi Değişir mi?

Abstract

Aim: Hand-foot-mouth disease (HFMD); fever is an enteroviral rash disease of childhood, progressing with skin and mucous lesions. Mean platelet volume (MPV) may be a more sensitive index than platelet count as an indicator of clinical interest in various disorders. In this study; We tried to find answers to the questions of whether MPV levels change in HFMD and can it be a guide in determining the future finding such as onychomedosis. Material and Methods: Retrospective demographic data, complaints and physical examination findings and complete blood count parameters of 52 patient sand 48 healthy controls who applied to the Department of Pediatrics in our hospital between 2018 and 2019 were evaluat. Results: The mean age of the patients was 3.3 ± 2.5 years, while it was 3.2 ± 2.6 years in the control group. The male and female percent of the patient and control groups were respectively 59.6% -40.4% and 60.4% -39.6%. There was no difference in age and gender between the groups. It was observed that the patients most frequently applied in May-June (63.6%). The most common complaint was rash (Şekil 1). En sık görülen başvuru şikayeti; el ve/veya ayaklarda döküntü (%100), ateş (%76,9) ve oral aft (%80,7) idi. Dermatolojik muayenede lezyonlar hastaların %92,9’unda el ve avuç içinde, %80,2’sinde ayaklarda, %72,5’inde ağız içinde ve %52,5’inde gluteal bölge, kol ve/veya bacaklarda izlendi. Ortalama ateş 37,6±0,8°C (100%), oral aphthae, (80.7%) and fever (76.9%). Four of the patients (7.6%) were hospitalized for various reasons. While the mean leukocyte value of patients who under went whole blood examination was 10459 ± 3485/ mm 3 , this rate was 6900 ± 2175 / mm 3 (p=0.019) in the healthy group. The mean MPV value in the patient and control groups were respectively 7.02 ± 1.49 fL, and 8.1 ± 1.2 fL (p=0.001). There was no difference between age, gender, diagnosis and MPV values between the patients who developed nail findings and those who did not (p=0.36). Conclusion: MPV value was found to be significantly lower than the control group. Therefore, we think that this value can also be used to predict patients who have not yet developed a rash.