Is Familial Mediterranean fever a risk factor for Malignant Peritoneal Mesothelioma: a Case Presentation and Literature Review

Abstract

Ozet Abstract Ailesel Akdeniz atesi (AAA) ates ve serozal inflamasyon ile karakterize kalitsal bir hastaliktir. Maling mezotelyoma (MM) primer olarak plevranin daha az yaygin olarak da periton, perikard ve tunika vaginalisin bir tumorudur. MM, AAA hastalarinda cok nadirdir ve aralarindaki iliski acik degildir. MM ve AAA arasinda az sayida vaka calismalarinda bir iliski rapor edilmistir. Bu noktada, biz daha once AAA tanisi olan karin agrisi ve siskinlik sikayetleri ile basvuran 51 yasinda bir Turk erkek hasta rapor ediyoruz ve MM ile AAA arasindaki tartismali iliskiyi literatur degerlendirmesi ile ortaya koyuyoruz. Familial Mediterranean fever (FMF) is an inherited disorder characterized by episodes of fever and serosal inflammation. Malignant mesothelioma (MM) is a primary tumor of the pleura and less commonly of the peritoneum, pericardium and tunica vaginalis. MM is very rare in patients with FMF and its association is unclear. An association between MM and FMF was reported in a small number of previous case studies. Herein we report the case of a 51-year-old Turkish male patient with a previous diagnosis of FMF presenting with abdominal pain and distension which were found to be due to MM and discuss their association by means of a literature review.