Analysis of Differences in Clinical Index between Lung Cancer Patients with or without Metastasis

Abstract

Lung cancer is a malignant disease with high morbidity and mortality. Early prediction of its metastasis is of great clinical significance. A total of 447 clinical indexes from 2847 lung cancer patients with and without metastasis were evaluated and after screening using non-parametric statistical tests. Twenty-one clinical examination indexes were identified that differed significantly between patients with and without metastasis. Tumour markers, nutritional status, immune system parameters, erythrocyte content, erythrocyte morphology and blood viscosity differed significantly between patients with and without metastasis. Among these indexes, the carcinoembryonic antigen index was the most significant. At present, there is a lack of highly specific biomarkers for lung cancer metastasis. The clinical indexes identified in this study can be used as key indicators of lung cancer metastasis during late follow-up.