Survival Analysis of HIV/AIDS Patients Under ART Follow up in Attat Referral Hospital

Abstract

Background: The non-curable HIV/AIDS epidemic has become a serious health and development problem especially for developing country like Ethiopia despite using ART treatment. The antiretroviral treatment (ART) scale-up service has been a recent development in Ethiopia, but its impact on mortality has not been well investigated. This study aimed to analyze the survival time of HIV-positive patients under antiretroviral therapy (ART) and identifies associated risk factors in Attat Referral Hospital. Methods: A retrospective study was conducted to examine the survival of HIV/AIDS patients under ART at Attat Referral Hospitals. Total of 408 HIV/AIDS patients in ART from April 30, 2010 up to March 30, 2017 were included in the study. Cox proportional hazard model was employed to assess the survival of HIV/AIDS patients and the associated factors. Results: A total of 408 patients were followed for a survival mean time of 46 months. In the followed-up period, 121 (29.7%) patients dead and 287 (70.3%) patients were censored. Based on functional status of patients, higher mortality was significantly associated with bedridden (HR: 3.934) and Ambulatory (HR: 1.790). According to WHO stages the patients under ART follow up with stage- IV (HR: 7.277), stage-III (HR: 4.536) and stage-II (HR: 2.213) were high risk of dying than patients in stages-I and male patients are at high risk of death than females. Conclusions: This study found that the survival time of the HIV patient under ART follow-ups in Attat Referral Hospital of Guraghe zone was significantly associated with factors: functional status, Weight, Original Regimen, CD4 count and WHO stage.