Correlation between duration of untreated psychosis and working memory in early-onset psychotic disorders

Personalized Medicine in Psychiatry Pub Date : 2021-11-01 DOI:10.1016/j.pmip.2021.100084

Joko Cahyo Baskoro , Ivana Ariella Nita Hadi , Maulidia Ekaputri , Noorhana Setiawati Winarsih

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Abstract

Psychotic disorders are morbid mental disorders that impair working memory. Theory suggests that longer duration of untreated psychosis (DUP) results in worse working memory. However, results from previous studies are contradictory, with no study having been conducted in children. This study aims at finding out the association between duration of untreated psychosis and working memory in children. This is a cross-sectional study with 45 subjects. DUP was collected from medical records whereas working memory was measured using digit span backward raw score. Average digit span backward scores of subjects was 3.7 ± 1.18. Analysis using Spearman test showed no significant association (p = 0.128) between DUP and working memory. In conclusion, there is no association between DUP and working memory in children, therefore we recommend that psychiatrists pay attention to working memory impairment in all pediatric patients with psychotic disorders, regardless of their DUP.

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早发性精神病患者未治疗精神病持续时间与工作记忆的相关性

精神障碍是损害工作记忆的病态精神障碍。理论表明，长期未治疗的精神病(DUP)会导致更差的工作记忆。然而，之前的研究结果是矛盾的，因为没有在儿童中进行过研究。本研究旨在探讨儿童精神病未治疗时间与工作记忆的关系。这是一项有45名受试者的横断面研究。DUP从医疗记录中收集，而工作记忆则使用数字广度向后原始评分来测量。被试的平均手指广度向后得分为3.7±1.18。Spearman检验显示，DUP与工作记忆无显著相关性(p = 0.128)。综上所述，DUP与儿童工作记忆之间没有关联，因此我们建议精神科医生关注所有精神病患者的工作记忆障碍，无论他们的DUP如何。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Personalized Medicine in Psychiatry

CiteScore

1.40

自引率

0.00%

发文量