Applications of physical therapy in the rehabilitation of patient with cerebral tumors: fourth ventricle infiltration in medulloblastoma

Iuliana Gabriela Cazac
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Abstract

Primitive brain tumors of the central nervous system are a major health problem. Most intraterritorial tumors affect functionally important areas of the brain and postoperative motor disability are unfavorable. Given its location, the fourth ventricle interposes between the cerebellum and the brainstem, therefore, a tumor that grows into the fourth ventricle, can produces a mechanical pressure on the nearby anatomical elements with specific symptoms. On a 15-year-old patient, diagnosed with medulloblastoma into fourth ventricle ( W.H.O. grade IV) molecular subgroups WnT, the initial tratament involved surgery to remove as much of the tumor as possible ( after two surgeries, some residual tumor was still left behind because it was too close to normal brain structures), then further treatment with chemotherapy and radiation therapy followed. After the treatment, the symptoms related (effects owing to the tumor itself and the effects of treatment) was: poor static and dynamic balance, truncal ataxia with impaired tandem gait, lack of the coordination and balance to walk safely and independently, (resulted from affecting the archicerebellum and paleocerebellum), appendicular ataxia (manifesting a difficulty with rapid alternating movements, finger-nose-finger), hypotonia, poor coordination (asynergy, dysmetria- resulted from the affected neocerebellum), dysarthria, nystagmus (due to pressure on the brainstem- vestibular syndrome). The purpose of this study was to restore lost motor skills, prevent complications, maximize function, and improve the quality of life.
物理治疗在脑肿瘤患者康复中的应用:髓母细胞瘤第四脑室浸润
中枢神经系统的原始脑肿瘤是一个主要的健康问题。大多数脑膜内肿瘤影响脑功能的重要区域,术后运动障碍是不利的。由于第四脑室的位置介于小脑和脑干之间,因此,肿瘤生长到第四脑室可对附近的解剖元件产生机械压力,并伴有特定症状。一名15岁的患者被诊断为第四脑室髓母细胞瘤(who分级IV)分子亚群WnT,最初的治疗包括手术切除尽可能多的肿瘤(两次手术后,一些残留的肿瘤仍被留下,因为它太靠近正常的大脑结构),然后接受进一步的化疗和放疗。治疗后,相关症状(肿瘤本身引起的影响和治疗效果)为:静态和动态平衡差,躯干共济失调伴串联式步态受损,缺乏安全独立行走的协调性和平衡性,(由于小脑和旧小脑的影响),附件共济失调(表现为快速交替运动困难,手指-鼻子-手指),张力低下,协调性差(不协调,测量障碍-由于受影响的新小脑),构音障碍,眼球震颤(由于脑干压力-前庭综合征)。这项研究的目的是恢复失去的运动技能,预防并发症,最大限度地发挥功能,提高生活质量。
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