Cardiomyopathies and heart failure in pregnancy

V. Regitz-Zagrosek
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Abstract

Treatment of cardiomyopathies (CM) and heart failure (HF) in pregnancy is based on the respective guidelines with some pregnancy-specific limitations. CM is a rare but serious cause of HF and currently the most frequent cause of maternal mortality in pregnancy. All forms of CM may occur in pregnancy, but peripartum CM (PPCM) is a specific and dangerous manifestation. Some new treatment options are arising based on its precise pathophysiology. Dilated CM (DCM) has a high risk of deterioration in pregnancy. In contrast, hypertrophic CM (HCM) is frequently tolerated well. Delivery should be well planned and some limitations on breastfeeding should be considered. HF with preserved EF (HFpEF) does presently not appear to be a major clinical problem in pregnancy.
妊娠期心肌病和心力衰竭
妊娠期心肌病(CM)和心力衰竭(HF)的治疗基于各自的指南,并有一些妊娠特异性的限制。CM是一种罕见但严重的心衰病因,也是目前妊娠期孕产妇死亡的最常见原因。所有形式的CM都可能发生在妊娠期,但围产期CM (PPCM)是一种特殊而危险的表现。基于其精确的病理生理机制,一些新的治疗方案应运而生。扩张型CM (DCM)在妊娠期恶化的风险很高。相比之下,肥厚性CM (HCM)通常耐受良好。分娩应精心计划,并应考虑母乳喂养的一些限制。HF伴保留EF (HFpEF)目前似乎不是妊娠期的主要临床问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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