Nootan Pandey, Daniel Keifenheim, M. Yoshida, Victoria A Hassebroek, Caitlin Soroka, Y. Azuma, D. J. Clarke
{"title":"Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases","authors":"Nootan Pandey, Daniel Keifenheim, M. Yoshida, Victoria A Hassebroek, Caitlin Soroka, Y. Azuma, D. J. Clarke","doi":"10.1083/jcb.201807189","DOIUrl":null,"url":null,"abstract":"To prevent chromosome missegregation, a metaphase checkpoint is activated when topoisomerase II is catalytically inhibited and DNA catenations persist. Pandey et al. dissect the key molecular events triggering this regulatory system.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"352 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.201807189","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
To prevent chromosome missegregation, a metaphase checkpoint is activated when topoisomerase II is catalytically inhibited and DNA catenations persist. Pandey et al. dissect the key molecular events triggering this regulatory system.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
