Chiral-Label-Free SERS Strategies for Discriminating Small Chiral Molecules

Abstract

Charge-transfer based surface-enhanced Raman scattering (SERS) is a promising tool for chiral-label-free discrimination of small molecules with the superiority of chirality signal amplification, synchronous distinction and identification, and high sensitivity. Such chiral-label-free SERS strategy need neither any chiral auxiliary nor circularly polarized light, which opens up a new way for chiral discrimination.