The NanoCytometer: Screening Cells Based on Cell Size

Abstract

Determination of cell size is crucial in many biomedical applications. Here, we show how resistive-pulse sensing and artificial pores can be used to detect and measure cell size accurately. Cell size is determined by measuring the change in resistance when an individual cell passes through the pore. As a proof-of-principle, we show that we are able to measure the change in size when cells undergo apoptosis