Microneedle arrays for drug delivery and fluid extraction

P. Zhang, G. Jullien
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引用次数: 15

Abstract

Fabrication results for a novel MEMS-based microneedle array are presented in this paper. The microneedle array design is introduced following a brief survey of previously published design techniques. The microneedle array is fabricated by employing a bi-mask technique to facilitate sharp tips, a cylindric body and side ports. The array has advantages over previously published results including ease of fabrication and bonding, and high needle density and robustness. In addition, the microneedle comprises side ports which minimizes the potential for clogging. This microneedle array can be used for fluid extraction and drug delivery systems; e.g., biological sampling, and insulin delivery into the human body.
用于药物输送和液体提取的微针阵列
本文介绍了一种新型mems微针阵列的制备结果。在对先前发表的设计技术进行简要调查之后,介绍了微针阵列的设计。微针阵列是通过采用双掩膜技术来制造的,以方便尖锐的尖端,圆柱体和侧端口。与先前发表的结果相比,该阵列具有优势,包括易于制造和粘合,高针密度和坚固性。此外,微针包括侧孔,最大限度地减少了堵塞的可能性。该微针阵列可用于流体提取和药物输送系统;例如,生物取样,胰岛素输送到人体内。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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