Management of Extramedullary Hematopoiesis: Why is a Hematologist’s Opinion Important

Abstract

Extramedullary Hematopoiesis (EMH) is a compensatory mechanism in response to ineffective hematopoiesis or stress erythropoiesis, in sites other than the bone marrow. The EMH often presents as pseudotumors and may be confused with other benign or malignant tumors. The cause of EMH often is an underlying hematopoietic disorder, and it may be adequately treated by treating the underlying cause. This will avoid unnecessary surgical interventions. Hence, knowledge of this entity is of utmost importance, and careful history, clinical examination and necessary investigations must be carried out before deciding the course of therapy.