Clinical Case of a Combination of Endocrine, Metabolic, and Mental Pathologies: Hypopituitarism Associated with Organic Personality Disorder

B. Marzoog
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Abstract

Psychiatric disorders are difficult to assess, diagnose, and treat in most cases. The present case describes an extremely rare psychological disorder in combination with metabolic and endocrine insufficiency. The condition of a 7-year-old child with inherited psychopathology from his father was found to be aggravated by his mother's alcoholism. The child was delivered in emergency from a primigravida/primipara mother due to preeclampsia and premature membrane rupture. The examinations involved clinical signs and symptoms and instrumental and laboratory findings. All laboratory results were compared with the normal range of the local laboratory. The results of the examination showed pronounced impairment in learning and controlling behavior, and communication, as well as moderate impairment in orientation. The future consequences and complications are poorly understood. Management guidelines for such complicated cases are underdeveloped. The child was managed by diet correction, potassium iodide and hormone replacement therapy, calcium supplement, nootropics with 2 courses per year, examination by a urologist and pediatric endocrinologist 2 times a year, and hospitalization after 6 months of treatment.
内分泌、代谢和精神疾病合并的临床病例:垂体功能减退与器质性人格障碍相关
在大多数情况下,精神疾病很难评估、诊断和治疗。本病例描述了一种极其罕见的心理障碍,并伴有代谢和内分泌功能不全。一名从父亲遗传精神病理的7岁儿童的病情因其母亲酗酒而恶化。由于先兆子痫和胎膜过早破裂,该儿童是在紧急情况下从初产妇/初产妇分娩的。检查包括临床体征和症状以及仪器和实验室结果。所有实验室结果与当地实验室的正常范围进行比较。检查结果显示在学习和控制行为、沟通方面有明显的障碍,在定向方面有中度障碍。未来的后果和并发症尚不清楚。针对此类复杂病例的管理指南尚不完善。患儿接受饮食矫正、碘化钾和激素替代疗法、补钙、益智药治疗,每年2个疗程,每年2次由泌尿科医生和儿科内分泌科医生检查,治疗6个月后住院。
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