Cell image reconstruction for a lens-free imaging system based on linear array Sensor

Abstract

This paper presents a novel lens-free microfluidic cell image acquisition system based on a linear array image sensor. A microfluidic chip is designed fabricated to control cells to pass through the microchannel steadily. Under the microfluidic chip, a linear array image sensor is placed to acquire the cell image. Then the cell image can be reconstructed, segmented and analyzed. The experimental results show that the system can effectively improve the quality of cell images. In view of the urgent need for point-of-care testing, this system is suitable for portable, low-cost, easy-to-use lens-free cell detection devices in the future.