Pediatric Sepsis Screen Accuracy: Comparison Of Two Reference Standards

Abstract

Background: Sepsis is a leading cause of morbidity and mortality among children, with early recognition and treatment impacting long-term health outcomes. While studies show screening interventions embedded in electronic health records can improve outcomes, evaluating such interventions is challenged by the lack of a universal reference standard of pediatric sepsis. Objective: Evaluate the test characteristics of an electronic sepsis screening algorithm (Figure 1) implemented in a pediatric emergency department (PED) using two reference standards for defining pediatric sepsis Design/Methods: Evaluation of a high-risk pediatric cohort treated in a PED, March-November …