[The effect of boric acid on the development of chick embryos treated at an early stage: preliminary results].

Abstract

10 mul of a 2% boric acid solution are injected in chick embryos at 28 hours of incubation. The nervous system is always affected in its anterior and middle region, with exencephaly and reduction in size of the neural tube. Microphtalmy is frequent. The posterior limbs can be likewise altered, leading sometimes to symelia. The histological study shows furthermore that the notochord is locally hypertrophic or missing, at the same level where the nervous system is altered.