Multi-Channel Near-Infrared Bandpass Mosaic Filter for Spectral Fundus Imaging

Honghao Tang, H. Takehara, Yusuke Horiki, M. Haruta, K. Sasagawa, J. Ohta, H. Tashiro
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Abstract

We previously reported a near-infrared (NIR) color fundus camera that can image the fundus without the use of mydriatic agents. Using this technology, pseudo-color images can be reconstructed from images in the three NIR wavelength bands. In this study, we designed and manufactured a five-wavelength bandpass mosaic filter for CMOS image sensors (CIS) by modifying the thickness of the middle layer of a multilayer thin-film structure based on the interference bandpass filter principle. It is possible to acquire information about all bands at all locations on the fundus by using the fixational movement of the human eye. Adapting a fabricated 5-channel CIS, we report the validity of high-spatial-resolution imaging by demosaicing and spectral resolution enhancement by deconvolution processing.
光谱眼底成像的多通道近红外带通马赛克滤波器
我们之前报道了一种近红外(NIR)彩色眼底相机,它可以在不使用散光剂的情况下对眼底进行成像。利用该技术,可以从三个近红外波段的图像重建伪彩色图像。在本研究中,我们基于干涉带通滤波器原理,通过改变多层薄膜结构中间层的厚度,设计并制造了一种用于CMOS图像传感器(CIS)的五波长带通马赛克滤波器。利用人眼的注视运动,可以获得眼底所有位置的所有带的信息。采用自制的5通道CIS,我们报道了通过反马赛克和反卷积处理提高光谱分辨率的高空间分辨率成像的有效性。
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