Aggregatibacter Actinomycetemcomitans: A Detrimental Microbial Pathogen: A Review

Abstract

Periodontal disease is a complex multifactorial inflammatory disease in which some specific microbial pathogens have been implicated in its pathophysiology namely Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Porphyromonasgingivalis. This review focuses on A. Actinomycetemcomitans, a gram negative micro-oraganisms and its role as one of the causative microorganisms of periodontitis, its interaction with the host, other oral micro flora and drugs including its association with extraoral diseases.