PDMS waveguide integrated microfluidic chip for the detection of fluorophore tagged polypeptides

Abstract

This work presents a novel method of fabrication of an optical microfluidic system by using polydimethylsiloxane (PDMS) and UV curable optical adhesive. An optical waveguide system including multiple waveguides and couplers were integrated with a microfluidic system by using soft lithography process. The developed LOC was demonstrated for the detection of fluorophore tagged polypeptides.