Application of Optical Coherence Tomography Angiography in Diagnosis of Primary Angle-Closure Glaucoma

Abstract

The changes of retinal microcirculation in the course of glaucoma disease have attracted the attention of many scholars. Optical coherence tomography angiography (OCTA) is a new non-invasive imaging technique, which can be used to evaluate the retinal and choroidal vascular system. Recent studies have shown that OCTA’s evaluation of retinal microcirculation changes is mainly in the para-optic area and macular area. In patients with glaucoma, whole-layer and RPC vessel density decreased significantly, which was correlated with disease severity. In the macular area, the blood vessel density decreased and the area without blood vessel increased significantly. Overall, it provides a new technique for the evaluation of retinal microcirculation in glaucoma and highlights the potential application of this new technique in the field of glaucoma. This paper reviews the progress of OCTA in the evaluation of retinal microcirculation in glaucoma from the aspects of the manifestations of retinal microcirculation and the image changes of retinal microcirculation in glaucoma, including the changes of microcirculation in the para-optic area of glaucoma, the changes of microcirculation in the macular area of glaucoma, the evaluation of influencing factors of microcirculation in the macular area and the para-optic area of glaucoma, and the comparison of diagnostic value.