The antioxidant effect of Brazil nut (Bertholletia excelsa) is influenced by a genetic superoxide-hydrogen peroxide imbalance in healthy humans

Abstract

Abbreviations: BN, Brazil nut; ROS, reactive oxygen species; Se, selenium; GPX, glutathione peroxidase; SNP, single nucleotide polymorphism; SOD, superoxide dismutase; V, valine; A, alanine; HP, hydrogen peroxide; HR, hydroxyl radical; PBMCs, peripheral-blood mononuclear cells; RFLP, restriction fragment length polymorphism; BMI, body mass index; CRP, C-reactive protein; TACO, table of food composition; DCFDA; dichlorofluoresceindiacetate; DCF, dichlorofluorescein; TBARS, thiobarbituric acid reactive substances; NO, nitric oxide