Dengue: An Overview of Pathogenesis and Analysis of Disease

Abstract

Dengue as a viral infection was or is a serious issue. With the time this viral infection changes within it’s environment. Researches are conducted to completely know the genome of dengue as well as it’s long lasting treatment. Both flaviviruses and mammalian cells produce NS1 and induce strong humoral responses in circulation. NS1 levels correlate with viral titer and can be used as a viremia marker. The disappearance of NS1 at high concentrations between low nanograms per milliliter and micrograms per milliliter was determined using numerical ELISA detection. NS1 levels as high as 600 nanograms per milliliter during secondary infection have been found to indicate high levels of severe disease within his first 72 hours of illness