Tear Film – Physiology and Disturbances in Various Diseases and Disorders

Ocular Surface Diseases - Some Current Date on Tear Film Problem and Keratoconic Diagnosis Pub Date : 2020-10-22 DOI:10.5772/intechopen.94142

D. Kopacz, Łucja Niezgoda, Ewa Fudalej, A. Nowak, P. Maciejewicz

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引用次数: 13

Abstract

The tear film is a thin fluid layer covering the ocular surface. It is responsible for ocular surface comfort, mechanical, environmental and immune protection, epithelial health and it forms smooth refractive surface for vision. The traditional description of the tear film divides it into three layers: lipid, aqueous and mucin. The role of each layer depends on the composition of it. Tear production, evaporation, absorption and drainage concur to dynamic balance of the tear film and leads to its integrity and stability. Nonetheless, this stability can be disturb in tear film layers deficiencies, defective spreading of the tear film, in some general diseases and during application of some general and/or topical medications. Dry eye disease is the result of it. In this review not only physiology of the tear film is presented. Moreover, we would like to discuss the influence of various diseases and conditions on the tear film and contrarily, spotlight tear film disorders as a manifestation of those diseases.

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泪膜-生理和干扰在各种疾病和障碍

泪膜是覆盖在眼表面的一层薄薄的液体。它负责眼表舒适、机械、环境和免疫保护、上皮细胞健康，并形成光滑的屈光面。对泪膜的传统描述将其分为三层:脂质层、水性层和粘蛋白层。每一层的作用取决于它的组成。泪液的产生、蒸发、吸收和排泄与泪液膜的动态平衡一致，从而保证了泪液膜的完整性和稳定性。然而，这种稳定性在泪膜层缺陷、泪膜扩散缺陷、一些一般疾病和一些一般和/或局部药物的应用中可能受到干扰。干眼症就是它的结果。在这篇综述中，不仅介绍了泪膜的生理学。此外，我们想讨论各种疾病和条件对泪膜的影响，相反，重点关注泪膜障碍作为这些疾病的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ocular Surface Diseases - Some Current Date on Tear Film Problem and Keratoconic Diagnosis

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