Unusual Presentation of a Renal Vein Invading Clear Cell Renal Cell Carcinoma with Non-Specific Gastrointestinal Symptomatology: A Case Report

Kadam Ss, S. Reddy, G Vidolkar, T. Kadam, Mumbai India Cytology Lab
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Abstract

Introduction: We are reporting a case of 62 year old male patient with central obesity presented with nonspecific gastrointestinal symptoms which was misdiagnosed and treated according to its symptomology. After complete evaluation found to have a large right Renal Cell Carcinoma (RCC) with involvement of right renal vein and later he underwent right radical nephrectomy. The presentation of RCC is variable and most of the times it presents with nonspecific symptoms. The classic triad of loin pain, hematuria and abdominal mass is found only in 4-17 % of cases. The incidence of RCC is 2.2% and mortality rate is 1.8% worldwide, in 2018. In India, its incidence is around 1.3% and mortality is 1.3% in 2018. It occurs predominantly in the 6th to 8th decade of life with median age at diagnosis around 64 years. Due to earlier detection of these tumors, the incidence has increased threefold than the mortality. One of the established risk factor for RCC is cigarette smoking. As the use of cigarette smoking increases the stage of RCC advances further.
肾静脉侵袭透明细胞肾细胞癌的不寻常表现与非特异性胃肠道症状:1例报告
我们报告一例62岁男性中心性肥胖患者,表现为非特异性胃肠道症状,根据其症状被误诊并治疗。经过全面的检查,发现他有一个大的右肾细胞癌(RCC)并累及右肾静脉,后来他接受了右肾根治性切除术。肾细胞癌的表现是多变的,大多数时候表现为非特异性症状。典型的腰痛、血尿和腹部肿块三联征仅在4- 17%的病例中发现。2018年,全球肾细胞癌发病率为2.2%,死亡率为1.8%。在印度,2018年的发病率约为1.3%,死亡率为1.3%。它主要发生在生命的第6至第8个十年,诊断时的中位年龄约为64岁。由于早期发现这些肿瘤,发病率比死亡率增加了三倍。吸烟是肾癌的已知危险因素之一。随着吸烟人数的增加,RCC阶段进一步推进。
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