F. Bersani, C. Franceschi, D. Monti, A. Bologni, C. Gatti, R. Cadossi, M. Nichelatti, G. Moschini, A. Cossarizza
{"title":"The effects of extremely low frequency pulsed electromagnetic fields (ELF) on human lymphocyte proliferation in vitro and DNA repair","authors":"F. Bersani, C. Franceschi, D. Monti, A. Bologni, C. Gatti, R. Cadossi, M. Nichelatti, G. Moschini, A. Cossarizza","doi":"10.1109/IEMBS.1988.95245","DOIUrl":null,"url":null,"abstract":"The effect of extremely-low-frequency electromagnetic fields on in-vitro mitogen-induced lymphocyte proliferation was studied in two groups of healthy subjects (23 and 85 years, mean ages). An increase of cell proliferation was observed to be much higher in the group of aged subjects. The effects depended on the mitogen dose and involved interleukin-2 production and/or utilization. The DNA repair capability and cell survival in the exposed cultures after gamma irradiation was also evaluated, and no genotoxic effect was found.<<ETX>>","PeriodicalId":227170,"journal":{"name":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"47 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1988-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1988.95245","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The effect of extremely-low-frequency electromagnetic fields on in-vitro mitogen-induced lymphocyte proliferation was studied in two groups of healthy subjects (23 and 85 years, mean ages). An increase of cell proliferation was observed to be much higher in the group of aged subjects. The effects depended on the mitogen dose and involved interleukin-2 production and/or utilization. The DNA repair capability and cell survival in the exposed cultures after gamma irradiation was also evaluated, and no genotoxic effect was found.<>