Pelvic Chondrosarcoma - The Role of the Biopsy and the Correlation Between the Histopathological Bioptic Diagnosis and the Excisional One

R. Popescu, S. Cuculici, Ș. Cristea
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Abstract

Abstract Chondrosarcoma is one of the most frequent malignant bone tumors. We included in the initial study population 110 patients with pelvis biopsies and the histopathological result of chondrosarcoma. We excluded the cases with incomplete data. Thirty-five in block resections were included in the final study population. In the rest of the cases, the surgery was not made because of many considerations (multiple metastases, patient’s refusal, and surgical contraindications). In three cases, discrepancies were noted between the grade of malignancy found after biopsy and the one confirmed through the surgical excision. This corresponds to a precision rate of 91,42 % (32/ 35) in the confirmation of chondrosarcoma. The accuracy of the histopathological diagnosis between low grade chondrosarcoma and high grade chondrosarcoma was of 94,27 % (33/ 35). We concluded that the image-guided biopsy is useful in determining the grade of malignancy of the chondrosarcoma and in the planning of the subsequent treatment. A multidisciplinary team (orthopaedic surgeon, radiologist, and pathologist) is needed to improve the diagnosis of the pelvic chondrosarcoma.
盆腔软骨肉瘤-活检的作用和组织病理活检诊断与切除之间的关系
软骨肉瘤是最常见的恶性骨肿瘤之一。我们在最初的研究人群中纳入了110例骨盆活检和软骨肉瘤组织病理学结果的患者。我们排除了资料不完整的病例。最终的研究人群中包括35例局部切除患者。在其余病例中,由于多种原因(多发性转移、患者拒绝和手术禁忌症),没有进行手术。在三个病例中,在活检后发现的恶性肿瘤等级与通过手术切除证实的恶性肿瘤等级之间存在差异。这相当于确认软骨肉瘤的准确率为91,42%(32/ 35)。低分级软骨肉瘤和高分级软骨肉瘤的病理诊断准确率为94.27%(33/ 35)。我们的结论是,图像引导下的活检在确定软骨肉瘤的恶性程度和制定后续治疗计划方面是有用的。需要一个多学科的团队(骨科医生、放射科医生和病理学家)来提高骨盆软骨肉瘤的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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