Two-wavelength excitation spectroscopy for non-invasive detection of the iron deficiency indicator zinc protoporphyrin IX

Abstract

Increased formation of fluorescent zinc protoporphyrin IX (ZnPP) inside erythrocytes indicates functional iron deficiency. Two-wavelength excitation spectroscopy detects ZnPP even through intact skin. Its suitability was successfully tested in women, surgical patients, infants and blood donors.