COMPARISON OF THE RESULTS OF CULTURING CELLS AND VIRUSES ON THE NEW SEPLIFE® LX-MC-DEX1 MICROCARRIER WITH EXISTING MICROCARRIERS

Abstract

microcarriers are small solid particles 90–350 µm in size, on the surface of which cells grow in the form of a monolayer. The two main properties of microcarriers are cell adhesion and high cell production. According to the results of a comparative study conducted on various parameters, it was determined that each microcarrier has its own advantages and disadvantages. In our study, the properties of SEPLIFE® LX-MC-dex1 and Cytodex 3 microcarriers were compared. According to the results of the studies, it was found that SEPLIFE® LX-MC-dex1, containing an artificial substance, is not inferior to Cytodex 3 microcarrier widely used in production in all properties and ease of use. The main advantage of the SEPLIFE® LX-MC-dex1 microcarrier is its cost effectiveness, i.e. it is 5 times cheaper than Cytodex 3. In this regard, the SEPLIFE® LX-MC-dex1 microcarrier was found to be cost-effective.