Superior Performance of Surface Plasmon Resonance Biosensor for Recognizing of DNA Hybridization

Abstract

In this paper, we demonstrate numerical sketching of high-performance graphene implicated Surface plasmon resonance (SPR) biosensor for biomedical inflictions especially the recognition of DNA Hybridization. This SPR biosensor can be recognized adsorption of DNA biomolecules into the sensing medium, which is usage Attenuated total reflection (ATR) technique to find out the refractive index (RI) varied due to the adsorption of different concentration of DNA biomolecules. By determining the right shift of SPR angle and variation of minimum reflectance (Rmin) distinguishes between hybridization and single nucleotide polymorphisms (SNP). The FDTD (Finite Difference Time Domain) technique is used for comprising between hybridization and SNP events by Lumerical FDTD Software.