Efficacy and Safety of Autologous Platelet Concentrate in the Treatment of Photoaging on the Back of the Hands

Abstract

Introduction: From the fourth decade of life (especially on the back of the hands) the skin becomes dry and brittle, spots appear, the venous network increases and soft tissues decrease. Objective: To evaluate the efficacy and safety of intradermal microinjection of autologous platelet concentrate (APC) in the treatment of rejuvenation of the back of the hands. Method: An observational, analytical and longitudinal study was carried out in 60 patients from the Hospital Clínico Quirúrgico: “Hermanos Ameijeiras”, in the period between March 1, 2017 and March 31, 2020. The treatment was applied monthly for 1 year. The final evaluation was carried out 3 months after the end of the treatment. Results: 51 women with an average age of 45 ± 4.3 years were treated. After treatment, there were significant changes in the Glogau photodamage scale (p = 0.012), in the global scale of aesthetic improvement (p <0.001) and in the scale of the degree of involvement of the volume of the hand (p = 0.018). The adverse events found were pain, inflammation and ecchymosis. The degree of satisfaction reported by the patients was good (26.6%) and very good (73.4%) (p <0.001). Conclusion: The autologous platelet concentrate proved to be effective and safe in reducing the signs of cutaneous aging on the back of the hands, associated with a high degree of patient satisfaction.