The Effect of Coffee Consumption on Acute Increased Blood Pressure in Normotensive Teens

Eunike Jennifer Tandiono, E. Budiyanti
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Abstract

Introduction: Caffeine has been known to elevate blood pressure. However, the effect of drinking coffee on blood pressure varied among studies. This study examines the impact of coffee on the acute response of blood pressure in a late adolescent with normal blood pressure. Method: This cross-sectional study with a cross-over design involving 16 male and late female adolescents. The intervention group subjects drank a glass of 200 ml of Robusta coffee (commercial brand), while the control group drank plain water. After a 7-day washout, the intervention group became the control group and vice versa. A paired t-test was applied to evaluate systolic blood pressure (SBP) and diastolic blood pressure (DBP) before and after the intervention. The significance was set at p<0.05. Results: SBP and DBP in the control group were unchanged (Δ0.8 and 0.6 mmHg, p=0.237 and 0.584, respectively). SBP and DBP in the intervention group were significantly elevated (Δ8.4 and 8.1 mmHg, p<0.01 and <0.01, respectively). Discussion: Our findings demonstrated that coffee increases SBP and DBP significantly in the late adolescent with normal BP. Increased sympathetic tones and blocking adenosine receptors are suggested to increase BP. However, some limitations were also found, so the results should be interpreted carefully. Conclusion: A 200 ml coffee (Robusta) increased SBP and DBP in late adolescents with normal blood pressure.   Keywords: Caffeine - Blood Pressure - Sympathetic Activity - Adenosine Receptor - Phosphodiesterase
饮用咖啡对正常血压青少年急性血压升高的影响
简介:众所周知,咖啡因可以升高血压。然而,喝咖啡对血压的影响在不同的研究中有所不同。这项研究考察了咖啡对血压正常的晚熟青少年血压急性反应的影响。方法:采用交叉设计的横断面研究,包括16名男性和晚期女性青少年。干预组受试者饮用一杯200毫升罗布斯塔咖啡(商业品牌),对照组饮用白开水。经过7天的洗脱期,干预组成为对照组,反之亦然。采用配对t检验评估干预前后的收缩压(SBP)和舒张压(DBP)。p<0.05为显著性。结果:对照组收缩压、舒张压无明显变化(Δ0.8、0.6 mmHg, p=0.237、0.584)。干预组患者收缩压、舒张压明显升高(Δ8.4、8.1 mmHg, p<0.01、<0.01)。讨论:我们的研究结果表明,在血压正常的青少年晚期,咖啡显著增加收缩压和舒张压。增加交感神经张力和阻断腺苷受体提示血压升高。然而,也发现了一些局限性,因此应该仔细解释结果。结论:200毫升咖啡(罗布斯塔)可增加血压正常的青少年晚期收缩压和舒张压。关键词:咖啡因血压交感神经活动腺苷受体磷酸二酯酶
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