Histopathological Changes in the Liver and Spleen of Albino Mouse, Mus musculus Linnaeus, 1758 Experimentally Infected with the Hydatid Cyst of Echinococcus granulosus (Batsch, 1786) and Its Treatments with Oxfendazole

A. Sadek
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Abstract

The present study was conducted as an attempt to chemically treat secondary hydatid cyst disease in the Albino mouse Mus musculus strain Balb/c. Oxfendazole (OFZ) was used at a concentration of 30 mg/kg, and the histopathological changes in the liver and spleen were examined. The efficiency of the drug was observed compared to the positive untreated control group. However, some histopathological changes were noticed in liver and spleen of the OFZ-treated mice.
实验感染细粒棘球绦虫(Batsch, 1786)的白化小鼠肝脾组织病理学变化及奥芬达唑治疗
本研究旨在尝试化学治疗白化小鼠Balb/c株继发性包虫病。用浓度为30 mg/kg的奥芬达唑(Oxfendazole, OFZ),观察肝、脾组织病理变化。与阳性未治疗对照组比较,观察该药的疗效。然而,ofz处理小鼠的肝脏和脾脏出现了一些组织病理学改变。
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