CELL DEATH AND ITS CONCEPT APPLIED IN GENERAL HEALTH AND MICRO-BIOLOGICAL ACTION: LITERATURE REVIEW

Centro de Pesquisas Avançadas em Qualidade de Vida Pub Date : 2020-07-08 DOI:10.36692/cpaqv-v12n2-50

Review, Gabriella Brandimarte Queiroz, Augusto Alberto, Toledo Neto, J. Lopes, Douglas Fernandes Silva

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Abstract

Cell death is an essential biological process for physiological growth and development. Therefore, this process has different types of cell death and the main three are: apoptosis, autophagy and necrosis. In addition, cell death is related to manifestations of various diseases and treatment of systemic diseases in the areas of general health, such as cancer and periodontitis, in addition to viruses. In this study, the importance of cell death for the organism and its relationship with various human diseases, such as the new coronavirus 2 respiratory syndrome (SARS-CoV-2), both in clinical manifestations and in possible treatments, such as tumor necrosis agents (anti -TNF), to improve the response rates of patients with inflammatory diseases or the importance of lymphocytic apoptosis, promoted by SARS-CoV-2 by increasing the expression of Fas. Through this study it was possible to identify the importance of cell death for the organism and how it can interfere in human diseases; thus, enable the biotechnological application in the development of specific drugs and therapies.

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细胞死亡及其概念在一般健康和微生物作用中的应用:文献综述

细胞死亡是生理生长发育的重要生物学过程。因此，这一过程有不同类型的细胞死亡，主要有三种:凋亡、自噬和坏死。此外，除病毒外，细胞死亡还与各种疾病的表现和一般健康领域的全身性疾病(如癌症和牙周炎)的治疗有关。在本研究中，细胞死亡对生物体的重要性及其与各种人类疾病的关系，如新冠状病毒2呼吸综合征(SARS-CoV-2)，无论是在临床表现还是在可能的治疗中，如肿瘤坏死剂(抗tnf)，以提高炎症性疾病患者的应答率，或SARS-CoV-2通过增加Fas表达促进淋巴细胞凋亡的重要性。通过这项研究，有可能确定细胞死亡对生物体的重要性，以及它如何干扰人类疾病;因此，使生物技术应用于特定药物和疗法的开发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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