Classification and grading of invasive squamous cell carcinoma of the uterine cervix.

Abstract

In 155 patients with invasive squamous carcinoma of the uterine cervix malignancy point grading was based on histologic examination of pretreatment biopsies. The observation time extended over 10 years. All patients received similar radiologic treatment. Tumour cell population and tumour-host relationship were estimated separately using eight parameters graded from 1 to 3. A fairly sharp border is distinguishable at 16 points, but an overlap occurred in both directions. The curable recurrences had 16 points or less. The necessity of deep biopsies for adequate grading was demonstrated.