Elektrospinning bidezko PCL nanozuntzen lorpena larruazal-birsorkuntzarako

Abstract

Skin ulcers are a serious threat to public health system, and, although wound healing is a natural process, a proper dressing can improve the healing process. In this work, platelet rich plasma (PRP) coated polycaprolactone (PCL) wound dressings have been designed by means of electrospinning. PCL is a biocompatible and biodegradable synthetic polymer. PRP, in turn, offers growth factors to the dressing, which are significant in the healing. To enable an effective addition of PRP, functionalization of PCL fibre meshes has been carried out by immersing them in alkaline dissolution of different concentrations. In this way, a novel wound dressing that aids in the regeneration of damaged skin layers has been developed.