Review of Leakage from a Linear Accelerator and Its Side Effects onCancer Patients

A. Kinsara, A. El-Gizawy, E. Banoqitah, Xuewei Ma
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引用次数: 2

Abstract

Radiation therapy using external beam radiation therapy (EBRT) is playing an important role for effective treatment of all kinds of tumors. Peripheral dose is the result of leakage and scatter from multileaf collimators devices (MLCs), counts for 2-10% of the maximum dose given to the patient, depending on the machine used and type of treatment. The present review reveals that despite of the recent advancements in linear accelerators (LINAC) and MLC design and technology, the remaining small amount of leakage (peripheral dose) of these devices still has significant side effects on patient’s life span and quality of life after treatment. Based on the findings in this review, it is suggested that introduction of additional effective and patient-specific shielding techniques would have great impact on reducing risk of radiating healthy cells and hence adversely side effects on cancer patients.
线性加速器泄漏及其对癌症患者的副作用综述
外束放射治疗(EBRT)在有效治疗各类肿瘤方面发挥着重要作用。外周剂量是多叶准直器(MLCs)泄漏和散射的结果,占给予患者最大剂量的2-10%,具体取决于所使用的机器和治疗类型。本综述显示,尽管线性加速器(LINAC)和MLC的设计和技术最近取得了进展,但这些装置的剩余少量泄漏(外周剂量)仍然对患者的寿命和治疗后的生活质量产生了显著的副作用。根据本综述的研究结果,建议引入额外的有效和针对患者的屏蔽技术,将对降低辐射健康细胞的风险产生重大影响,从而减少对癌症患者的不良副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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