The Study of Different Endometrial Pattern in Dysfunctional Uterine Bleeding of Women in Western Rajasthan

Abstract

Background: Dysfunctional uterine bleeding is one of the most frequently encountered conditions in gynaecological practice world over and is defined as bleeding from the uterine corpus that is abnormal in volume, regularity and /or timing and has been present for majority of the past 6 months. This study was done to evaluate histology of endometrium for identifying the endometrial causes of DUB. Material and Methods: This was a retrospective study done at Dr S N Medical College, Jodhpur, Rajasthan on 250 patients who presented with DUB from June 2020– September 2022. The endometrial changes were observed by reviewing and studying the histological slides, prepared through routine processing channels which includes fixation, grossing, tissue processing, dehydration, paraffin embedding, cutting and H&E staining procedures. Results: The commonest endometrial pattern was proliferative pattern in 145(58.00%) cases. Followed by secretary pattern in 34(13.60%), disordered proliferative pattern 19(7.60%). Cystic Dilatation11 (4.4%), Simple Endometrial Hyperplasia 9 (3.6%), Atrophic Changes 9(3.6%), Late Proliferative Pattern8 (3.2%), Early Secretory Pattern 6(2.4%), Hyperplasia without atypia5 (2%), Arias Stella reaction3 (1.2%), Cystic Hyperplasia1(0.4%). Conclusion: The incidence of proliferative pattern was significantly high in this study, suggesting an early presentation of these patients.