The Relation Between D-dimer Level and Chest X-Ray (CXR) Scoring in COVID-19 Patients:

Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on "Emergency Preparedness and Disaster Response during COVID 19 Pandemic" (ASMC 2021) Pub Date : 1900-01-01 DOI:10.2991/ahsr.k.210723.037

Tersia Viradanti, Yudith Yunia Kusmala

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Abstract

—Coronavirus disease is a kind of pneumonia cause by infection of SARS-CoV-2. In most cases, patients only get mild manifestation or even asymptomatic. Some patient can get severe disease, especially elderly people or someone with comorbid, leading to cytokines storm that triggers SIRS and induce coagulation dysregulation (marked by D-dimer elevation) so that increasing risk to get thrombosis. Recent pathology finding suggest that micro-thrombosis has contribution to ARDS due to lung’s fibrosis. We use a CXR scoring system to assess lung parenchyma involvement in COVID-19 patients and D-dimer level to see coagulopathy then performing an analysis to investigate the relationship between both. Based on the Spearman test, we find that there is a significant relationship between D-dimer level and CXR scores of COVID-19 patients describe as a positive correlation (p=0.023; r=0.358).

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新型冠状病毒肺炎患者d -二聚体水平与胸部x线评分的关系

冠状病毒病是一种由SARS-CoV-2感染引起的肺炎。在大多数情况下，患者只有轻微的表现，甚至无症状。部分患者病情严重，尤其是老年人或有合并症的患者，可引起细胞因子风暴，触发SIRS，诱发凝血功能失调(以d -二聚体升高为标志)，从而增加血栓形成的风险。近期病理发现提示肺纤维化引起的微血栓形成与ARDS有关。我们使用CXR评分系统评估COVID-19患者的肺实质受累情况和d -二聚体水平，以观察凝血功能病变，然后进行分析以调查两者之间的关系。基于Spearman检验，我们发现d -二聚体水平与COVID-19患者CXR评分呈显著正相关(p=0.023;r = 0.358)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on "Emergency Preparedness and Disaster Response during COVID 19 Pandemic" (ASMC 2021)

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