Applications of Raman Spectroscopy as an Non-Invasive Method in Pharmaceutical Analysis

Abstract

Spatially Offset Raman Spectroscopy (SORS) and Transmission Raman Spectroscopy (TRS) are methods for analysing bulk turbidly scattering materials such as powders, tablets, suspensions and other chemical mixtures, and provides non-invasive measurements with high selectivity and sensitivity. They can be effectively used for non-invasive probing of the content of pharmaceutical capsules and tablet and provides an analytical technique ideally suited for fast on-line process control monitoring applications in pharmaceutical industry where rapid, chemically specific bulk analysis is required