Air Pollution: a New Risk Factor for Developing Stroke

V. Demarin, S. Morović, F. Đerke
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Abstract

Many years scientist try to explore the connection between air pollution and its influence on human health and after numerous conducted researches they came up with the clear evidence that air pollution has a significant impact on overall health and especially on stroke. In the Global Burden of Disease Study, it has emerged as a significant contributor to the global stroke burden, especially in lowand middle-income countries. Furthermore, these and some other researches have suggested a closer link between air pollution and ischemic stroke, due to huge diversity of the results of numerous other studies, for drawing definitive conclusions, further research is still needed. Due to the complexity of stroke with its types and subtypes, the results of their reaction to air pollution differ. Some studies have shown the link between cardioembolic stroke and AP, others with SAH but not with intracerebral haemorrhage. There was a suggestion that nitrogen dioxide exposure might be associated with stroke caused by small vessel disease, while other studies are not reporting any association of AP and the risk of ischemic stroke. In some studies, AP was more affecting young adults and in some, it was more pronounced in women. Some studies reported a more clear link between AP and recent stroke in patients with other risk factors like diabetes and previous stroke. Studies have varied by the concentration and types of pollutants studied, which vary geographically, as well as by duration to AP exposure being shortor long-term, and in some studies being present only during warm seasons. Regulations have improved air quality in many countries in Europe and the United States, resulting in greater life expectancy, which highlights the continued importance of further efforts in that direction.
空气污染:中风发生的新危险因素
多年来,科学家们试图探索空气污染与其对人类健康的影响之间的联系,经过大量的研究,他们得出了明确的证据,即空气污染对整体健康有重大影响,尤其是对中风。在全球疾病负担研究中,它已成为全球中风负担的一个重要因素,特别是在低收入和中等收入国家。此外,这些研究和其他一些研究表明,空气污染与缺血性中风之间存在更密切的联系,由于许多其他研究的结果差异很大,为了得出明确的结论,还需要进一步的研究。由于中风类型和亚型的复杂性,它们对空气污染的反应结果不同。一些研究表明心脏栓塞性中风与AP之间存在联系,其他研究表明与SAH有关,但与脑出血无关。有一项研究表明,二氧化氮暴露可能与小血管疾病引起的中风有关,而其他研究并未报道AP与缺血性中风风险之间的任何关联。在一些研究中,AP对年轻人的影响更大,而在一些研究中,AP在女性中更为明显。一些研究报告称,在有其他危险因素(如糖尿病和既往中风)的患者中,AP与近期中风之间存在更明确的联系。研究因所研究的污染物的浓度和类型而有所不同,这些污染物在地理上各不相同,接触AP的时间较短,长期较长,在一些研究中只在温暖的季节出现。条例改善了欧洲和美国许多国家的空气质量,从而延长了预期寿命,这突出了在这方面进一步努力的继续重要性。
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