P152 Pneumocystis jiroveci pneumonia prophylaxis in patients treated with mycophenolate mofetil for interstitial lung disease

Abstract

changes appear in the interstitium. The basic underlying pathology being inflammation in the alveolar epithelium, aerosol scintigraphy assesses the rate of clearance at this level, thereby helping with early diagnosis. Aims 1. To assess the alveolar capillary permeability in dcSSc patients using Tc 99m DTPA aerosol scintigraphy. 2. To identify the association of DTPA clearance rates with spirometry, HRCT, six-minute walk distance (6MWD), modified rodnan skin score (mRSS), nail fold capillaroscopy (NFC), serum KL–6, SP-D, CA 15–3 and Saint George’s Respiratory Questionnaire (SGRQ).