Evaluation of dosage effect of position numbers in IMRT for breast cancer

Yuan Zhao, Wei Peng
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Abstract

Objective To evaluate the dosage effect of position numbers in intensity-modulated radiotherapy plan (IMRT) for breast cancer. Method A 56 year old patient with breast cancer was selected and treated by IMRT in this study. According to the images of the position verification, the target dosage and organ at risk (OAR) were calculated and verified in detail. Results When the position number was 5, the doses of the target and OARs were CTV 48.8Gy, PTV 48.2Gy, spinal cord 27.5Gy, lung 5.5Gy with V20<11.5%, heart 16.0Gy with V10<33.7%, femoral head 38.2Gy. Although all the doses met the prescription of radiotherapeutic physicist, however, the doses of OAR closed to the dosage limitation. In order the decrease the doses of OAR, the number of position verification increased to 7. Therefore the doses of OAR decreased significantly. Conclusion The positioning error can be decreased by increasing the number of position verification.
乳腺癌IMRT中位置数的剂量效应评价
目的探讨位号在乳腺癌调强放疗计划中的剂量效应。方法选择1例56岁乳腺癌患者,采用IMRT治疗。根据位置验证图像,对靶剂量和危及器官(OAR)进行了详细的计算和验证。结果当位置数为5时,靶区剂量为CTV 48.8Gy, PTV 48.2Gy,脊髓27.5Gy,肺5.5Gy, V20<11.5%,心脏16.0Gy, V10<33.7%,股骨头38.2Gy。虽然所有的剂量都符合放射治疗物理学家的处方,但OAR的剂量接近剂量限制。为了减小桨叶剂量,位置验证次数增加到7次。因此,OAR的剂量明显降低。结论通过增加位置验证次数,可以减小定位误差。
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